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The renal clearance of hydrochlorothiazide in patients with regular renal operate is 285mL/min. Individuals by using a creatinine clearance of 31-80mL/min have a mean hydroxychlorothiazide renal clearance of 75mL/min, and sufferers that has a creatinine clearance of ?30mL/min have a median hydroxychlorothiazide renal clearance of 17mL/min.Their pri